The story is based on the drug squad crushing drug-related crimes, with the blood and tears of an ordinary drug police officer. It is mainly about the emergence of a new type of drug with extremely high purity and great damage: Hongbing, in the city A. Ma Zhiqiang (played by He Gang), deputy captain of the city's anti-drug squad, dives deep into the world of drugs with an experienced group of drug traffickers to investigate the production and transportation line of the new drug.